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Amino Acid Sequence
1 to 450
His tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 20% Glycerol, 20mM Tris Cl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0
- C SRC
- C SRC kinase
- C src Tyrosine Kinase
Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.
Expressed in lung and macrophages.
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
Contains 1 protein kinase domain.
Contains 1 SH2 domain.
Contains 1 SH3 domain.
Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.
Cytoplasm. Cell membrane. Mainly cytoplasmic, also present in lipid rafts.
Information by UniProt
References for Recombinant Human CSK protein (ab82187)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"