Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMRPQERMVGELRDLSPDDPQVQKAAQAAVA SYNMGSNSIYYFRDTHIIKAQSQLVAGIKYFLTMEMGSTDCRKTRVTGDH VDLTTCPLAAGAQQEKLRCDFEVLVVPWQNSSQLLKHNCVQM
    • Molecular weight
      16 kDa including tags
    • Amino acids
      29 to 149
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab109966 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab109966 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • CST 6
    • CST6
    • Cystatin 6
    • Cystatin E
    • Cystatin E/M
    • Cystatin M
    • Cystatin M/E
    • Cystatin-6
    • Cystatin-E
    • Cystatin-M
    • Cystatin6
    • CystatinE
    • CystatinM
    • Cysteine proteinase inhibitor
    • CYTM_HUMAN
    see all
  • Function
    Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
  • Tissue specificity
    Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.
  • Sequence similarities
    Belongs to the cystatin family.
  • Post-translational
    modifications
    Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3µg ab109966.

References

ab109966 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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