Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.
Belongs to the cystatin family.
Substrate for transglutaminases. Acts as an acyl acceptor but not as an acyl donor.