Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      SEIPKGKQKAQLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPGI PGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGIDLGKIAECTFTK MRSNSALRVLFSGSLRLKCRNACCQRWYFTFNGAECSGPLPIEAIIYLDQ GSPEMNSTINIHRTSSVEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGW NSVSRIIIEELPK
    • Molecular weight
      24 kDa including tags
    • Amino acids
      31 to 243
    • Additional sequence information
      Mature protein. NCBI Accession No. NP_612464.1.

Specifications

Our Abpromise guarantee covers the use of ab187209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    >95% by SDS-PAGE .
    Purification method: 6xHis tag / Immobilized-metal affinity chromatography (IMAC).
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Reconstitute for long term storage.

    pH: 8.00
    Preservative: 1.7% Imidazole
    Constituents: 0.33% Sodium phosphate, 2.9% Sodium chloride, 1.74% Arginine, 0.0078% Beta mercaptoethanol

General Info

  • Alternative names
    • Collagen triple helix repeat containing 1
    • Collagen triple helix repeat containing protein 1
    • Collagen triple helix repeat-containing protein 1
    • CTHR1_HUMAN
    • Cthrc1
    • NMTC1 protein
    • Protein NMTC1
    see all
  • Function
    May act as a negative regulator of collagen matrix deposition.
  • Tissue specificity
    Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells.
  • Sequence similarities
    Contains 1 collagen-like domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt

Images



  • Predicted band size : 26 kDa

    Western blot analysis of ab187209.

  • 15% SDS-PAGE analysis of ab187209 stained with Coomasie Blue.

References

ab187209 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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