Recombinant human CXCL14 protein (ab50043)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceSKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE

Specifications

Our Abpromise guarantee covers the use of ab50043 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityBiological Activity : Determined by it's ability to chemoattract activated monocytes using a concentration range of 1.0-10.0 ng/ml.
  • Applications

    Western blot

    SDS-PAGE

    Functional Studies

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • 1110031L23Rik
    • 1200006I23Rik
    • AI414372
    • BMAC
    • bolekine
    • BRAK
    • C-X-C motif chemokine 14
    • Chaemokine, CXC motif, ligand 14
    • Chemokine (C-X-C motif) ligand 14
    • Chemokine BRAK
    • CXC chemokine in breast and kidney
    • CXCL14
    • CXL14_HUMAN
    • JSC
    • Kec
    • Kidney-expressed chemokine CXC
    • KS1
    • MGC10687
    • MGC124510
    • MGC90667
    • MIP 2 gamma
    • MIP-2G
    • MIP2G
    • MIP2gamma
    • NJAC
    • PRO273
    • PSEC0212
    • Scyb14
    • Small Inducible Cytokine B14
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 14 (BRAK)
    • Small Inducible Cytokine subfamily B, member 14
    • Small-inducible cytokine B14
    • UNQ240
    see all
  • FunctionPotent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactive for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.
  • Tissue specificityExpressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte-derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Cellular localizationSecreted.
  • Information by UniProt

Recombinant human CXCL14 protein images

  • Anti-CXCL14 antibody (ab36622) at 1 µg/ml + Recombinant human CXCL14 protein (ab50043) at 0.1 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 12 minutes

References for Recombinant human CXCL14 protein (ab50043)

ab50043 has not yet been referenced specifically in any publications.

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For reconstitution, please centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
For extended storage, it is recommended to further dilute in a buffer conta...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"