Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceNEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQLLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP
    • Amino acids49 to 137

Associated products

Specifications

Our Abpromise guarantee covers the use of ab50175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityBiological Activity : Determined by it's ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml.
  • Applications

    SDS-PAGE

    Functional Studies

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute to 1mg/ml in sterile water.

General Info

  • Alternative names
    • C-X-C motif chemokine 16
    • Chemokine (C X C motif) ligand 16
    • Chemokine, CXC motif, ligand 16
    • CXC chemokine ligand 16
    • Cxcl16
    • CXCLG16
    • CXL16_HUMAN
    • Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
    • SCYB16
    • Small inducible cytokine B16 precursor
    • Small-inducible cytokine B16
    • SR-PSOX
    • SRPSOX
    • Transmembrane chemokine CXCL16
    • UNQ2759/PRO6714
    see all
  • FunctionActs as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
  • Tissue specificityExpressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localizationCell membrane. Secreted. Also exists as a soluble form.
  • Information by UniProt

References for Recombinant human CXCL16 protein (ab50175)

ab50175 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"