The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesBest use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.31% Glutathione
C-X-C chemokine receptor type 2
Chemokine (CXC) receptor 2
High affinity interleukin-8 receptor B
IL 8 receptor type 2
IL 8R B
IL-8 receptor type 2
IL8 receptor type 2
Interleukin 8 Receptor B
Interleukin 8 receptor, beta
Interleukin 8 receptor, type 2
FunctionReceptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Post-translational modificationsPhosphorylated upon ligand binding; which is required for desensitization.