Recombinant Human Cyclin E1 protein (ab119719)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      73 kDa including tags
    • Amino acids
      1 to 410

Associated products

Specifications

Our Abpromise guarantee covers the use of ab119719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    Purity tested by densitometry.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 25% Glycerol, 0.79% Tris HCl, 0.88% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.003% DTT, 0.002% PMSF

General Info

  • Alternative names
    • CCNE
    • Ccne1
    • CCNE1_HUMAN
    • cyclin E variant ex5del
    • cyclin E variant ex7del
    • Cyclin E1
    • Cyclin Es
    • Cyclin Et
    • CyclinE
    • G1/S specific cyclin E
    • G1/S-specific cyclin-E1
    see all
  • Function
    Essential for the control of the cell cycle at the G1/S (start) transition.
  • Tissue specificity
    Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
  • Sequence similarities
    Belongs to the cyclin family. Cyclin E subfamily.
  • Post-translational
    modifications
    Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Recombinant Human Cyclin E1 protein images

  • SDS Page analysis of ab119719

References for Recombinant Human Cyclin E1 protein (ab119719)

ab119719 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119719.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up