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Source Baculovirus infected Sf9 cells
Amino Acid Sequence
Molecular weight 73 kDa including tags
Amino acids 1 to 410 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 90
% SDS-PAGE. Purity tested by densitometry.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 0.79% Tris HCl, 0.88% Sodium chloride, 0.31% Glutathione, 0.003% EDTA, 0.003% DTT, 0.002% PMSF
Function Essential for the control of the cell cycle at the G1/S (start) transition.
Tissue specificity Highly expressed in testis and placenta. Low levels in bronchial epithelial cells.
Sequence similarities Belongs to the cyclin family. Cyclin E subfamily.
Post-translational modifications Phosphorylation of Thr-395 by GSK3 and of Ser-399 by CDK2 accelerates degradation via the ubiquitin proteasome pathway. Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization Nucleus.
Information by UniProt
Recombinant Human Cyclin E1 protein images
References for Recombinant Human Cyclin E1 protein (ab119719)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"