Recombinant Human Cystatin SN protein (ab116170)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGSMWSPKEEDRIIPGGIYNADLNDEWVQR ALHFAISEYNKATKDDYYRRPLRVLRARQQTVGGVNYFFDVEVGRTICTK SQPNLDTCAFHEQPELQKKQLCSFEIYEVPWENRRSLVKS RCQES
    • Molecular weight
      17 kDa including tags
    • Amino acids
      21 to 141
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116170 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab116170 is purified by using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 10% Glycerol, 0.58% Sodium chloride, 0.32% Tris HCl, 0.03% DTT

General Info

  • Alternative names
    • CST1
    • Cystain SAI
    • Cystain-SA-I
    • Cystatin 1
    • Cystatin-1
    • Cystatin-SN
    • Cystatin1
    • Cysteine proteinase inhibitor, type 2 family
    • CYTN
    • CYTN_HUMAN
    • Salivary cystatin SA1
    • Salivary cystatin-SA-1
    see all
  • Function
    Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.
  • Tissue specificity
    Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid.
  • Sequence similarities
    Belongs to the cystatin family.
  • Cellular localization
    Secreted.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab116170 at approximately 16.9kDa (3µg).

References

ab116170 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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