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Product name Recombinant Human Cytochrome P450 2A6 protein
Protein length Protein fragment Description
Source Wheat germ
Amino Acid Sequence
Sequence LGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGL ARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR
Molecular weight 37 kDa including tags
Amino acids 395 to 494 Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notes Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.3% Glutathione, 0.79% Tris HCl
Coumarin 7 hydroxylase
Function Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
Tissue specificity Liver.
Sequence similarities Belongs to the cytochrome P450 family.
Cellular localization Endoplasmic reticulum membrane. Microsome membrane.
Information by UniProt
Recombinant Human Cytochrome P450 2A6 protein images
References for Recombinant Human Cytochrome P450 2A6 protein (ab114776)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"