Recombinant Human Cytochrome P450 2B6 protein (ab114648)

Overview

  • Product name
    Recombinant Human Cytochrome P450 2B6 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRG LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGK IAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEA QCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLN LFYQTFSLISSVFGQLFELFSGFLTYFPGAHRQVYKNLQEINAYIGHSVE KHRETLDPSAPKDLIDTYLLHMEEEKSNAHSEFSHQNLNLNTLSLFFAGT ETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTE AVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPH YFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFF TTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR
    • Molecular weight
      80 kDa including tags
    • Amino acids
      1 to 491

Associated products

Specifications

Our Abpromise guarantee covers the use of ab114648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 1,4 cineole 2 exo monooxygenase
    • 11B1
    • CP2B6_HUMAN
    • CPB 6
    • CPB6
    • CYP 2B6
    • CYP IIB6
    • CYP2B
    • CYP2B6
    • CYP2B7
    • CYP2B7P
    • CYPIIB6
    • Cytochrome P450 2B6
    • Cytochrome P450 family 2 subfamily B
    • Cytochrome P450 family 2 subfamily B polypeptide 6
    • Cytochrome P450 IIB1
    • Cytochrome P450 phenobarbital inducible
    • Cytochrome P450 subfamily IIB (phenobarbital inducible)
    • Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6
    • Cytochrome P450 subfamily IIB polypeptide 6
    • EFVM
    • IIB1
    • P450
    • P450 IIB1
    • P450IIB1
    see all
  • Function
    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • Tissue specificity
    Expressed in liver, lung and heart right ventricle.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Post-translational
    modifications
    Phosphorylation is accompanied by a decrease in enzyme activity.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

Images

  • ab114648 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab114648 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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