Recombinant Human Cytokeratin 13 protein (ab112315)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVS CGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLL TGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPER DYSPYYKTIEELRDKILTATIENNRVILEIDNARLAVDDFRLKYENELAL RQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVA ETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ EIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGR RTSDVRRP
    • Molecular weight
      76 kDa including tags
    • Amino acids
      1 to 458
    • Tags
      GST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112315 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

General Info

  • Alternative names
    • 47 kDa cytokeratin
    • CK-13
    • CK13
    • Cytokeratin 13
    • Cytokeratin-13
    • K13
    • K1C13_HUMAN
    • Ka13
    • Keratin
    • Keratin 13
    • keratin type I cytoskeletal 13
    • Keratin-13
    • Krt-1.13
    • Krt1-13
    • KRT13
    • MGC161462
    • MGC3781
    • type I cytoskeletal 13
    • Type I keratin Ka13
    • WSN2
    see all
  • Tissue specificity
    Expressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
  • Involvement in disease
    Defects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
  • Sequence similarities
    Belongs to the intermediate filament family.
  • Post-translational
    modifications
    O-glycosylated; glycans consist of single N-acetylglucosamine residues.
  • Information by UniProt

Recombinant Human Cytokeratin 13 protein images

  • ab112315 on a 12.5% SDS-PAGE stained with coomassie blue

References for Recombinant Human Cytokeratin 13 protein (ab112315)

ab112315 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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