Recombinant Human Cytokeratin 13 protein (ab112315)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP13646
    • SpeciesHuman
    • SequenceMSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVS CGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLL TGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPER DYSPYYKTIEELRDKILTATIENNRVILEIDNARLAVDDFRLKYENELAL RQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEF SNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHAKS AELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVA ETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQ EIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGR RTSDVRRP
    • Molecular weight76 kDa including tags
    • Amino acids1 to 458
    • TagsGST tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab112315 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • FormLiquid
  • Additional notesBest use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

General Info

  • Alternative names
    • 47 kDa cytokeratin
    • CK-13
    • CK13
    • Cytokeratin 13
    • Cytokeratin-13
    • K13
    • K1C13_HUMAN
    • Ka13
    • Keratin
    • Keratin 13
    • keratin type I cytoskeletal 13
    • Keratin-13
    • Krt-1.13
    • Krt1-13
    • KRT13
    • MGC161462
    • MGC3781
    • type I cytoskeletal 13
    • Type I keratin Ka13
    • WSN2
    see all
  • Tissue specificityExpressed in some epidermal sweat gland ducts (at protein level) and in exocervix, esophagus and placenta.
  • Involvement in diseaseDefects in KRT13 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
  • Sequence similaritiesBelongs to the intermediate filament family.
  • Post-translational
    modifications
    O-glycosylated; glycans consist of single N-acetylglucosamine residues.
  • Information by UniProt

Recombinant Human Cytokeratin 13 protein images

  • ab112315 on a 12.5% SDS-PAGE stained with coomassie blue

References for Recombinant Human Cytokeratin 13 protein (ab112315)

ab112315 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab112315.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"