The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Specific activity: >0.8 units/ml, One unit will oxidatively deaminate 1.0 µmole of D-alanine to pyruvate per minute at pH 8.5 at 37C, in the presence of catalase.
It is inactive on the naturally occurring L-amino acids.
% SDS-PAGE. ab86700 is purified using conventional chromatography techniques.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 20% Glycerol, 20mM Tris HCl, pH 8.0
This product is an active protein and may elicit a biological response in vivo, handle with caution.
FunctionRegulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
Sequence similaritiesBelongs to the DAMOX/DASOX family.