Recombinant Human D4 GDI protein (ab124592)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSHMTE KAPEPHVEED DDDELDSKLN YKPPPQKSLK ELQEMDKDDE SLIKYKKTLL GDGPVVTDPK APNVVVTRLT LVCESAPGPI TMDLTGDLEA LKKETIVLKE GSEYRVKIHF KVNRDIVSGL KYVQHTYRTG VKVDKATFMV GSYGPRPEEY EFLTPVEEAP KGMLARGTYH NKSFFTDDDK QDHLSWEWNL SIKKEWTE
    • Molecular weight
      49 kDa including tags
    • Amino acids
      1 to 201

Associated products

Specifications

Our Abpromise guarantee covers the use of ab124592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    ab124592 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 7.40
    Constituents: 89% PBS, 10% Glycerol

General Info

  • Alternative names
    • Arhgdib
    • D4
    • D4 GDP dissociation inhibitor
    • GDIA 2
    • GDIA2
    • GDID 4
    • GDID4
    • GDIR2_HUMAN
    • GDP dissociation inhibitor D4
    • LY GDI
    • Ly-GDI
    • LYGDI
    • MGC108926
    • RAP1GN1
    • Rho GDI 2
    • Rho GDI beta
    • Rho GDI2
    • Rho GDP dissociation inhibitor (GDI) beta
    • Rho GDP dissociation inhibitor 2
    • Rho GDP dissociation inhibitor beta
    • Rho GDP-dissociation inhibitor 2
    • Rho-GDI beta
    • RhoGDI2
    see all
  • Function
    Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
  • Tissue specificity
    Detected in bone marrow, thymus and spleen.
  • Sequence similarities
    Belongs to the Rho GDI family.
  • Cellular localization
    Cytoplasm, cytosol.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab124592 (3µg).

References

ab124592 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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