Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      Protein contains a GST tag.

Associated products

Specifications

Our Abpromise guarantee covers the use of ab39943 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

General Info

  • Alternative names
    • Arhgdib
    • D4
    • D4 GDP dissociation inhibitor
    • GDIA 2
    • GDIA2
    • GDID 4
    • GDID4
    • GDIR2_HUMAN
    • GDP dissociation inhibitor D4
    • LY GDI
    • Ly-GDI
    • LYGDI
    • MGC108926
    • RAP1GN1
    • Rho GDI 2
    • Rho GDI beta
    • Rho GDI2
    • Rho GDP dissociation inhibitor (GDI) beta
    • Rho GDP dissociation inhibitor 2
    • Rho GDP dissociation inhibitor beta
    • Rho GDP-dissociation inhibitor 2
    • Rho-GDI beta
    • RhoGDI2
    see all
  • Function
    Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
  • Tissue specificity
    Detected in bone marrow, thymus and spleen.
  • Sequence similarities
    Belongs to the Rho GDI family.
  • Cellular localization
    Cytoplasm, cytosol.
  • Information by UniProt

References

ab39943 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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