This product is an active protein and may elicit a biological response in vivo, handle with caution.
DAP kinase 1
Death Associated Protein Kinase 1
Death-associated protein kinase 1
FunctionCalcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Contains 10 ANK repeats. Contains 1 death domain. Contains 1 protein kinase domain.
Post-translational modificationsUbiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.
Cellular localizationCytoplasm. Colocalizes with the actin filament system.