Recombinant human DCAMKL1 protein (ab101777)

Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      110 kDa including tags
    • Amino acids
      1 to 740

Specifications

Our Abpromise guarantee covers the use of ab101777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    The Specific activity of ab101777 was determined to be 3.4 nmol/min/mg.
  • Applications

    Western blot

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab188554 (CaMKII peptide) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Calcium/calmodulin-dependent protein kinase type I-like CPG16
    • CL1
    • CLICK1
    • Cpg16
    • DCDC3A
    • Dcl
    • Dclk
    • Dclk1
    • DCLK1_HUMAN
    • Doublecortin domain-containing protein 3A
    • Doublecortin-like and CAM kinase-like 1
    • Doublecortin-like kinase 1
    • KIAA0369
    • Serine/threonine-protein kinase DCAMKL1
    • Serine/threonine-protein kinase DCLK1
    see all
  • Function
    Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
  • Tissue specificity
    In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 2 doublecortin domains.
    Contains 1 protein kinase domain.
  • Information by UniProt

Images

  • SDS-PAGE showing ab101777 at approximately 110kDa.
  • The Specific activity of ab101777 was determined to be 3.4 nmol/min/mg.

References

ab101777 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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