Overview

  • Product name
    Recombinant Human DCPS protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMADAAPQLGKRKRELDVEEAHAASTEE KEAGVGNGTCAPVRLPFSGFR LQKVLRESARDKIIFLHGKVNEASGDG DGEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQ LNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSI QWVYNILDKKAEADRIVFENPDPSD GFVLIPDLKWNQQQLDDLYLIAI CHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLP SY YHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTF ALRADDPLLKLLQEAQQS
    • Molecular weight
      41 kDa including tags
    • Amino acids
      1 to 337
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab113138 was purified using conventional chromatography.
  • Form
    Liquid
  • Additional notes


  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
    Mix suspension via gentle inversion before use.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT

General Info

  • Alternative names
    • 1700001E16Rik
    • AA408441
    • ARS
    • DCPS
    • DCPS_HUMAN
    • DCS 1
    • DCS-1
    • DCS1
    • Decapping enzyme scavenger
    • heat shock-like protein 1
    • Hint 5
    • Hint related 7meGMP directed hydrolase
    • HINT-5
    • Hint-related 7meGMP-directed hydrolase
    • HINT5
    • Histidine triad protein member 5
    • homolog of C. elegans 7meGMP-directed hydrolase dcs-1
    • HSL1
    • HSPC015
    • m7GpppX diphosphatase
    • MGC124934
    • mRNA decapping enzyme
    • OTTMUSP00000042220
    • Scavenger mRNA decapping enzyme DcpS
    • Scavenger mRNA-decapping enzyme DcpS
    see all
  • Function
    Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
  • Tissue specificity
    Detected in liver, brain, kidney, testis and prostate.
  • Sequence similarities
    Belongs to the HIT family.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of (3µg)

References

ab113138 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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