Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMAAESLPFSFGTLSSWELEAWYEDLQEVLS SDENGGTYVSPPGNEEEESKIFTTLDPASLAWLTEEEPEPAEVTSTSQSP HSPDSSQSSLAQEEEEEDQGRTRKRKQSGHSPARAGKQRMKEKEQENERK VAQLAEENERLKQEIERLTREVEATRRALIDRMVNLHQA
    • Molecular weight
      21 kDa including tags
    • Amino acids
      1 to 169
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab117195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Purity
    > 90 % SDS-PAGE.
    ab117195 is purified by proprietary chromatographic techniques and sterile filtered. Purity greater than 90.0% as determined by analysis by RP-HPLC and analysis by SDS-PAGE.
  • Form
    Liquid
  • Additional notes
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 20% Glycerol, 0.32% Tris HCl

General Info

  • Alternative names
    • C/EBP homologous protein
    • C/EBP Homology Protein
    • C/EBP zeta
    • C/EBP-homologous protein
    • C/EBP-homologous protein 10
    • CCAAT/enhancer binding protein homologous protein
    • CEBPZ
    • CHOP
    • CHOP 10
    • CHOP-10
    • CHOP10
    • DDIT 3
    • DDIT-3
    • Ddit3
    • DDIT3_HUMAN
    • DNA Damage Inducible Transcript 3
    • DNA damage-inducible transcript 3 protein
    • GADD 153
    • GADD153
    • Growth Arrest and DNA Damage Inducible Protein 153
    • Growth arrest and DNA damage inducible protein GADD153
    • Growth arrest and DNA damage-inducible protein GADD153
    • MGC4154
    see all
  • Function
    Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA.
  • Involvement in disease
    Note=A chromosomal aberration involving DDIT3 is found in a patient with malignant myxoid liposarcoma. Translocation t(12;16)(q13;p11) with FUS.
  • Sequence similarities
    Belongs to the bZIP family.
    Contains 1 bZIP domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab117195 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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