Overview

  • Product nameRecombinant Human DDIT4 protein
  • Protein lengthFull length protein

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids1 to 232

Specifications

Our Abpromise guarantee covers the use of ab40031 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Inhibition Assay

    SDS-PAGE

    Western blot

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

General Info

  • Alternative names
    • DDIT4
    • DDIT4_HUMAN
    • Dig2
    • DNA damage inducible transcript 4
    • DNA damage inducible transcript 4 protein
    • DNA damage-inducible transcript 4 protein
    • FLJ20500
    • HIF 1 responsive protein RTP801
    • HIF 1 responsive RTP801
    • HIF-1 responsive protein RTP801
    • Protein regulated in development and DNA damage response 1
    • REDD-1
    • REDD1
    • RTP801
    see all
  • FunctionInhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.
  • Tissue specificityBroadly expressed, with lowest levels in brain, skeletal muscle and intestine. Up-regulated in substantia nigra neurons from Parkinson disease patients (at protein level).
  • Sequence similaritiesBelongs to the DDIT4 family.
  • Cellular localizationCytoplasm.
  • Information by UniProt

Recombinant Human DDIT4 protein images

  • SDS-PAGE: Analysis of DDIT4 Recombinant Protein

References for Recombinant Human DDIT4 protein (ab40031)

ab40031 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"