Recombinant human DDR2 protein (ab96401) (ab96401)



  • NatureRecombinant
  • SourceBaculovirus
  • Amino Acid Sequence
    • AccessionQ16832
    • SpeciesHuman
    • Molecular weight70 kDa including tags
    • Amino acids467 to 855


Our Abpromise guarantee covers the use of ab96401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityThe specific activity was determined to be 48 nmol/min/mg.
  • Applications


    Functional Studies

  • Purity 90 % .
    Purity was determined to be >90% by densitometry.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 10mM Glutathione, 0.25mM DTT, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • CD167 antigen-like family member B
    • CD167b
    • CD167b antigen
    • Cell migration inducing protein 20
    • DDR 2
    • DDR2
    • DDR2_HUMAN
    • Discoidin domain containing receptor 2
    • Discoidin domain receptor 2
    • Discoidin domain receptor family member 2
    • discoidin domain receptor tyrosine kinase 2
    • Discoidin domain-containing receptor 2
    • discoidin domain-containing receptor tyrosine kinase 2
    • Hydroxyaryl protein kinase
    • MIG20a
    • Migration inducing gene 16 protein
    • Neurotrophic tyrosine kinase
    • Neurotrophic tyrosine kinase receptor related 3
    • NTRKR 3
    • NTRKR3
    • Receptor protein tyrosine kinase TKT
    • Receptor protein-tyrosine kinase TKT
    • Receptor related 3
    • receptor-related 3
    • TKT
    • TYRO 10
    • TYRO10
    • Tyrosine kinase receptor related to neurotrophic TRK
    • Tyrosine protein kinase TYRO 10
    • Tyrosine protein kinase TYRO10
    • Tyrosine-protein kinase TYRO10
    • Tyrosylprotein kinase
    see all
  • FunctionThis tyrosine kinase receptor for fibrillar collagen mediates fibroblast migration and proliferation. Contributes to cutaneous wound healing.
  • Tissue specificityThe major 10 kDa transcript is expressed in high levels in heart and lung, less in brain, placenta, liver, skeletal muscle, pancreas, and kidney.
  • Involvement in diseaseDefects in DDR2 are the cause of spondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL) [MIM:271665]. A bone disease characterized by short-limbed dwarfism, a narrow chest with pectus excavatum, brachydactyly in the hands and feet, a characteristic craniofacial appearance and premature calcifications. The radiological findings are distinctive and comprise short long bones throughout the skeleton with striking epiphyses that are stippled, flattened and fragmented and flared, irregular metaphyses. Platyspondyly in the spine with wide intervertebral spaces is observed and some vertebral bodies are pear-shaped with central humps, anterior protrusions and posterior scalloping.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    Contains 1 F5/8 type C domain.
    Contains 1 protein kinase domain.
  • Cellular localizationMembrane.
  • Information by UniProt

Recombinant human DDR2 protein (ab96401) images

  • Kinase Assay demonstrating specific activity of ab96401.
  • SDS-PAGE showing ab96401 at approximately 70kDa.

References for Recombinant human DDR2 protein (ab96401) (ab96401)

ab96401 has not yet been referenced specifically in any publications.

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