The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
DEAD (Asp-Glu-Ala-Asp) box helicase 21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
DEAD box protein 21
Nucleolar RNA helicase 2
Nucleolar RNA helicase Gu
Nucleolar RNA helicase II
RNA helicase II/Gu alpha
Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription. Involved in rRNA processing.
Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain.
The two enzymatic activities reside in two separate domains, the helicase in the N-terminus and the foldase in the C-terminus. The 3 X 5 AA repeats seem to be critical for the RNA folding activity.