Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      71 kDa including tags
    • Amino acids
      1 to 388

Specifications

Our Abpromise guarantee covers the use of ab112427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.31% Glutathione

General Info

  • Alternative names
    • DGAT2
    • DGAT2_HUMAN
    • Diacylglycerol O acyltransferase like protein 2
    • Diacylglycerol O-acyltransferase 2
    • Diacylglycerol O-acyltransferase homolog 2
    • Diacylglycerol O-acyltransferase homolog 2 (mouse)
    • Diacylglycerol O-acyltransferase-like protein 2 isoform 1
    • Diglyceride acyltransferase 2
    • DKFZp686A15125
    • GS1999full
    • HMFN1045
    see all
  • Function
    Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation.
  • Tissue specificity
    Predominantly expressed in liver and white adipose tissue. Expressed at lower level in mammary gland, testis and peripheral blood leukocytes. Expressed in sebaceous glands of normal skin but decreased psoriatic skin.
  • Pathway
    Glycerolipid metabolism; triacylglycerol biosynthesis.
  • Sequence similarities
    Belongs to the diacylglycerol acyltransferase family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt

Images

  • ab112427 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab112427 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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