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Source Escherichia coli
Amino Acid Sequence
Sequence MGSSHHHHHH SSGLVPRGSH MEGSLEREAP AGALAAVLKH SSTLPPESTQ VRGYDFNRGV NYRALLEAFG TTGFQATNFG RAVQQVNAMI EKKLEPLSQD EDQHADLTQS RRPLTSCTIF LGYTSNLISS GIRETIRYLV QHNMVDVLVT TAGGVEEDLI KCLAPTYLGE FSLRGKELRE NGINRIGNLL VPNENYCKFE DWLMPILDQM VMEQNTEGVK WTPSKMIARL GKEINNPESV YYWAQKNHIP VFSPALTDGS LGDMIFFHSY KNPGLVLDIV EDLRLINTQA IFAKCTGMII LGGGVVKHHI ANANLMRNGA DYAVYINTAQ EFDGSDSGAR PDEAVSWGKI RVDAQPVKVY ADASLVFPLL VAETFAQKMD AFMHEKNED
Molecular weight 43 kDa including tags
Amino acids 1 to 369
Tags His tag N-Terminus Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Purity > 95
% SDS-PAGE. ab116440 was purified by proprietary chromatographic techniques and filter sterilized.
Additional notes ab116440 is stable at 4°C for 30 days, it should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Please see notes section.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 20% Glycerol
Function Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Pathway Protein modification; eIF5A hypusination.
Sequence similarities Belongs to the deoxyhypusine synthase family.
Post-translational modifications Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
References for Recombinant Human DHPS protein (ab116440)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"