Overview

  • Product name
    Recombinant Human DHRS4 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGSHMHKAGLLGLCARAWNSVRMASSGMTR RDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATL QGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSI MDVTEEVWDKTLDINVKAPALMTKAVVPEMMHKAGLLGLCARAWNSVRMA SSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQEKRG GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL APGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA SYITGETVVVGGGTPSRL
    • Molecular weight
      32 kDa including tags
    • Amino acids
      1 to 278
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116155 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Mass Spectrometry

    SDS-PAGE

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 85 % SDS-PAGE.
    ab116155 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.50
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.02% DTT

General Info

  • Alternative names
    • AI043103
    • AI790593
    • Carbonyl reductase
    • CR
    • D14Ucla2
    • Dehydrogenase/reductase SDR family member 4
    • Dhrs4
    • DHRS4_HUMAN
    • humNRDR
    • mouNRDR
    • NADPH dependent carbonyl reductase/NADP retinol dehydrogenase
    • NADPH dependent retinol dehydrogenase/reductase
    • NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase
    • NADPH-dependent retinol dehydrogenase/reductase
    • NDRD
    • NRDR
    • Peroxisomal short chain alcohol dehydrogenase
    • Peroxisomal short-chain alcohol dehydrogenase
    • PHCR
    • PRO1800
    • PSCD
    • RRD
    • SCAD-SRL
    • SCADSRL
    • Short chain dehydrogenase/reductase family member 4
    • Short-chain dehydrogenase/reductase family member 4
    • UNQ851
    see all
  • Function
    Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha-dicarbonyl compounds with aromatic rings, such as pyrimidine-4-aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4-hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones.
  • Tissue specificity
    Isoform 1 is predominantly expressed in normal cervix (at protein level). Isoform 4 is expressed in some neoplastic cervical tissues, but not in normal cervix (at protein level). Isoform 5 and isoform 6 are expressed in a few neoplastic cervical tissues.
  • Sequence similarities
    Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  • Cellular localization
    Peroxisome. Isoform 1 is peroxisomal, while isoform 4 is not.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab116155 at approximately 32.1kDa (3µg).

References

ab116155 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab116155.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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