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Recombinant Human DIRC2 protein
Full length protein
Amino Acid Sequence
MGSRWSSEEERQPLLGPGLGPGLGASWRSREAAAAALPAAVPGPGRVYGR RWLVLLLFSLLAFVQGLVWNTWGPIQNSARQAYGFSSWDIALLVLWGPIG FLPCFAFMWLLDKRGLRITVLLTSFLMVLGTGLRCIPISDLILKRRLIHG GQMLNGLAGPTVMNAAPFLSTTWFSADERATATAIASMLSYLGGACAFLV GPLVVPAPNGTSPLLAAESSRAHIKDRIEAVLYAEFGVVCLIFSATLAYF PPRPPLPPSVAAASQRLSYRRSVCRLLSNFRFLMIALAYAIPLGVFAGWS GVLDLILTPAHVSQVDAGWIGFWSIVGGCVVGIAMARFADFIRGMLKLIL LLLFSGATLSSTWFTLTCLNSITHLPLTTVTLYASCILLGVFLNSSVPIF FELFVETVYPVPEGITCGVVTFLSNMFMGVLLFFLTFYHTELSWFNWCLP GSCLLSLLLILCFRESYDRLYLDVVVSV
1 to 478
proprietary tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.31% Glutathione, 0.79% Tris HCl
Electrogenic metabolite transporter.
Ubiquitous. Expressed in proximal tubular cells of the kidney.
Involvement in disease
Note=A chromosomal aberration involving DIRC2 has been found in a family with renal carcinoma. Translocation t(2;3)(q35;q21).
Belongs to the major facilitator superfamily.
Cleaved in lysosomes by cathepsin L between Leu-214 and Ala-261, generating a N-glycosylated N-terminal and a non-glycosylated C-terminal fragment.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"