The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityInhibits adipogenesis of 3T3L1 cells. Induces Hes1 in 3T3L-1 cells.
Endotoxin level< 0.100 Eu/µg
% SDS-PAGE. ab108952 is 0.2µm filtered.
Inhibits adipogenesis of 3T3L1 cells. Induces Hes1 in 3T3L-1 cells.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: PBS, pH 7.2
ReconstitutionReconstitute in distilled water
Delta (Drosophila) like 1
Delta like 1
Delta like 1 (Drosophila)
Delta like 1 protein
Delta like protein 1
Delta like protein 1 precursor
Delta, Drosophila, homolog of 1
Delta-like protein 1
Drosophila Delta homolog 1
FunctionActs as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
Tissue specificityExpressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.
Induction of Hes1 with the treatment of ab108952.
A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5ug/ml of ab108952 as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-Mouse Hes1 or GAPDH.
Functional Studies - DLL1 protein (ab108952)
Interaction of Human Notch1 with Human DLL1. HEK293 cells transfected with a human Notch1 or a Human GITR ligand expressing vector were incubated with 25 ug/ml of Human GITR-Fc or ab108952). Cells were stained with anti-Human IgG(Fc specific) FITC conjugate for DLL1-Fc binding.
References for Recombinant Human DLL1 protein (ab108952)
has not yet been referenced specifically in any publications.
Publishing research using ab108952? Please let us know so that we can cite the reference in this datasheet.
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