Recombinant Human DNase I protein (ab152343)

Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MRGMKLLGALLALAALLQGAVSLKIAAFNIQTFGETKMSNATLVSYIVQI LSRYDIALVQEVRDSHLTAVGKLLDNLNQDAPDTYHYVVSEPLGRNSYKE RYLFVYRPDQVSAVDSYYYDDGCEPCGNDTFNREPAIVRFFSRFTEVREF AIVPLHAAPGDAVAEIDALYDVYLDVQEKWGLEDVMLMGDFNAGCSYVRP SQWSSIRLWTSPTFQWLIPDSADTTATPTHCAYDRIVVAGMLLRGAVVPD SALPFNFQAAYGLSDQLAQAISDHYPVEVMLK
    • Molecular weight
      58 kDa including tags
    • Amino acids
      1 to 282

Specifications

Our Abpromise guarantee covers the use of ab152343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Deoxyribonuclease 1
    • Deoxyribonuclease I
    • Deoxyribonuclease-1
    • Deoxyribonuclease1
    • DeoxyribonucleaseI
    • DNAS1_HUMAN
    • DNASE 1
    • DNase I
    • DNase I lysosomal
    • DNASE1
    • DNaseI
    • DNL 1
    • DNL1
    • Dornase alfa
    • DRNI
    • FLJ38093
    • Human urine deoxyribonuclease I
    see all
  • Function
    Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization.
  • Tissue specificity
    Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva.
  • Sequence similarities
    Belongs to the DNase I family.
  • Cellular localization
    Secreted. Nucleus envelope. Secretory protein, stored in zymogen granules and found in the nuclear envelope.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab152343 stained with Coomassie Blue.

References

ab152343 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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