Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMGSHMEPLRVLELYSGVGGMHHALRESCIP AQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMS PPCQPFTRIGRQGDMTDSRTNSFLYILDILPRLQKLPKYILLENVKGFEV SSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPF QAPGQVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDGSIQCSGKD AILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRY ALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNL SQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNS LNVHVVAKLIKILYE
    • Molecular weight
      47 kDa including tags
    • Amino acids
      1 to 391
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124566 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 90 % SDS-PAGE.
    ab124566 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • dDNMT
    • DmMT 2
    • DmMT2
    • DNA (cytosine 5 ) methyltransferase 2
    • DNA (cytosine 5) methyltransferase like protein 2
    • DNA (cytosine-5)-methyltransferase-like protein 2
    • DNA 5 cytosine methyltransferase
    • DNA methyltransferase 2
    • DNA methyltransferase homolog HsaIIP
    • DNA MTase homolog HsaIIP
    • Dnmt 2
    • Dnmt2
    • M.HsaIIP
    • MHsaIIP
    • nmt 2
    • nmt2
    • OTTHUMP00000045198
    • PuMet
    • RNMT 1
    • RNMT1
    • TRDMT 1
    • TRDMT_HUMAN
    • TRDMT1
    • tRNA (cytosine 5 ) methyltransferase
    • tRNA (cytosine(38)-C(5))-methyltransferase
    • tRNA aspartic acid methyltransferase 1
    • tRNA aspartic acid methyltransferase 1 variant 1
    • tRNA aspartic acid methyltransferase 1 variant 2
    • tRNA aspartic acid methyltransferase 1 variant 3
    • tRNA aspartic acid methyltransferase 1 variant 4
    • tRNA aspartic acid methyltransferase 1 variant 5
    • tRNA aspartic acid methyltransferase 1 variant 8
    see all
  • Function
    Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
  • Tissue specificity
    Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes.
  • Sequence similarities
    Belongs to the C5-methyltransferase family.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • 15% SDS-PAGE analysis of 3 µg ab124566.

References

ab124566 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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