Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab79662 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Specific Activity: 22.4 pmol/min/µg.
  • Applications

    Functional Studies

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Dipeptidyl peptidase 8
    • Dipeptidyl peptidase IV-related protein 1
    • Dipeptidyl peptidase VIII
    • Dipeptidylpeptidase 8
    • DP8
    • DPP VIII
    • Dpp8
    • DPP8_HUMAN
    • DPRP-1
    • DPRP1
    • EC 3.4.14.5
    • MSTP141
    • Prolyl dipeptidase DPP8
    see all
  • Function
    Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.
  • Tissue specificity
    Ubiquitously expressed, with highest levels in testis, placenta, prostate, muscle and brain.
  • Sequence similarities
    Belongs to the peptidase S9B family. DPPIV subfamily.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • Specific Activity 22.4 pmol/min/µg. Determined using 10 µM Ala-Pro-AMC substrate.
  • SDS-PAGE showing ab79662 at approximately 129kDa (4µg).
  • Anti-DPP8 antibody (ab96470) at 1/1000 dilution + Recombinant human DPP8 protein (ab79662) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 3 minutes

References

ab79662 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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