The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
> 1.000 Eu/µg
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at 4°C prior to reconstitution. Store at -20°C or -80°C.
Information available upon request.
It is recommended to reconstitute in 100 µl sterile deionized water to a final concentration of 1 mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly recommended for further dilution and long term storage. After reconstitution store under sterile conditions for 1 month at 4°C - 8°C or 3 months at -20°C to -80°C.
Cytotoxic TRAIL receptor
Death receptor 4
NF related apoptosis-inducing ligand receptor 1
TNF receptor superfamily member 10a
TNF-related apoptosis-inducing ligand receptor 1
TRAIL receptor 1
Tumor necrosis factor receptor superfamily member 10A
Tumor necrosis factor receptor superfamily member 10a variant 2
Tumor necrosis factor receptor superfamily, member 10a
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells.
Contains 1 death domain. Contains 3 TNFR-Cys repeats.