The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
130 kDa transcriptional co activator
133 kDa transcriptional co activator
Activator recruited cofactor 130 kDa component
Activator-recruited cofactor 130 kDa component
Cofactor required for Sp1 transcriptional activation subunit 3
Cofactor required for Sp1 transcriptional activation subunit 3 130kDa
Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator
CRSP 130 kD subunit
CRSP complex subunit 3
Mediator complex subunit 23
Mediator of RNA polymerase II transcription subunit 23
Protein sur-2 homolog
Transcriptional co activator CRSP 130
Transcriptional co activator CRSP130
Transcriptional coactivator CRSP130
Vitamin D3 receptor interacting protein
Vitamin D3 receptor interacting protein complex 130 kDa component
Vitamin D3 receptor-interacting protein complex 130 kDa component
Required for transcriptional activation subsequent to the assembly of the preinitiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling.
Belongs to the Mediator complex subunit 23 family.