Recombinant Human DUSP1 protein (ab114331)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionP28562
    • SpeciesHuman
    • SequenceMVMEVGTLDA GGLRALLGER AAQCLLLDCR SFFAFNAGHI AGSVNVRFST IVRRRAKGAM GLEHIVPNAE LRGRLLAGAY HAVVLLDERS AALDGAKRDG TLALAAGALC REARAAQVFF LKGGYEAFSA SCPELCSKQS TPMGLSLPLS TSVPDSAESG CSSCSTPLYD QGGPVEILPF LYLGSAYHAS RKDMLDALGI TALINVSANC PNHFEGHYQY KSIPVEDNHK ADISSWFNEA IDFIDSIKNA GGRVFVHCQA GISRSATICL AYLMRTNRVK LDEAFEFVKQ RRSIISPNFS FMGQLLQFES QVLAPHCSAE AGSPAMAVLD RGTSTTTVFN FPVSIPVHST NSALSYLQSP ITTSPSC
    • Molecular weight66 kDa including tags
    • Amino acids1 to 367

Specifications

Our Abpromise guarantee covers the use of ab114331 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • CL 100
    • CL100
    • Dual Specificity Phosphatase 1
    • Dual specificity protein phosphatase 1
    • Dual specificity protein phosphatase hVH1
    • DUS1_HUMAN
    • DUSP 1
    • Dusp1
    • HVH1
    • MAP kinase phosphatase 1
    • Mitogen-activated protein kinase phosphatase 1
    • MKP-1
    • MKP1
    • Protein tyrosine phosphatase CL100
    • Protein-tyrosine phosphatase CL100
    • PTPN10
    • Serine/threonine specific protein phosphatase
    • VH1
    see all
  • FunctionDual specificity phosphatase that dephosphorylates MAP kinase ERK2 on both 'Thr-183' and 'Tyr-185'.
  • Tissue specificityExpressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 rhodanese domain.
    Contains 1 tyrosine-protein phosphatase domain.
  • Information by UniProt

Recombinant Human DUSP1 protein images

  • ab114331 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue

References for Recombinant Human DUSP1 protein (ab114331)

ab114331 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. The activity for ab 113160 is as follows:

Specific activity: >1,750 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme hydrolyzing 1 nmole of p-nitrophenyl phosphate (pNPP) per minute ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"