Recombinant Human DUSP3 protein (ab113160)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMSGSFELSVQDLNDLLSDGSGCYSLPSQPC NEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHNTNANFYKDS GITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRS PTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEG KLKP
    • Molecular weight
      23 kDa including tags
    • Amino acids
      1 to 205
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113160 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab113160 was purified by using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.04% DTT, 0.88% Sodium chloride

General Info

  • Alternative names
    • Dual specificity phosphatase 3
    • Dual specificity protein phosphatase 3
    • Dual specificity protein phosphatase VHR
    • DUS3_HUMAN
    • DUSP3
    • Serine/threonine specific protein phosphatase
    • Vaccinia H1-related phosphatase
    • Vaccinia virus phosphatase VH1 related
    • VHR
    see all
  • Function
    Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt

Images

  • ab113160 at 3 µg analysed by 15% SDS PAGE.

References

ab113160 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for contacting us. The activity for ab 113160 is as follows:

Specific activity: >1,750 units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme hydrolyzing 1 nmole of p-nitrophenyl phosphate (pNPP) per minute ...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up