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Amino Acid Sequence
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
Deoxyuridine 5' triphosphate nucleotidohydrolase, nuclear isoform
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Found in a variety of tissues.
Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.
Belongs to the dUTPase family.
Phosphorylation in mature T-cells occur in a cell cycle-dependent manner.
Mitochondrion and Nucleus.
Information by UniProt
Recombinant Human DUT protein images
References for Recombinant Human DUT protein (ab99388)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"