The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
230 kDa bullous pemphigoid antigen
230/240 kDa bullous pemphigoid antigen
Bullous pemphigoid antigen
Bullous pemphigoid antigen 1
Dystonia musculorum protein
Hemidesmosomal plaque protein
RelevanceCytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh.
Isoform 3: plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity.
Isoform 6: required for bundling actin filaments around the nucleus By similarity.
Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.
Cellular localizationCytoplasm › cytoskeleton.
Recombinant Human Dystonin protein images
SDS-PAGE - Dystonin protein (Human) (ab117061)
12.5% SDS-PAGE showing ab117061 at approximately 36.63 kDa.
Stained with Coomassie Blue.
References for Recombinant Human Dystonin protein (ab117061)
has not yet been referenced specifically in any publications.
Publishing research using ab117061? Please let us know so that we can cite the reference in this datasheet.
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