Estrogen receptor binding fragment associated gene 9 protein
Estrogen receptor binding site associated antigen 9
estrogen receptor binding site associated, antigen, 9
Estrogen receptor-binding fragment-associated gene 9 protein
Receptor binding cancer antigen expressed on SiSo cells
Receptor-binding cancer antigen expressed on SiSo cells
FunctionMay participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
Tissue specificityWidely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs.
DomainThe coiled coil domain is necessary for the homodimerization.
Cellular localizationGolgi apparatus membrane. According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain.