The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
ER degradation enhancer, mannosidase alpha like 3
ER degradation enhancing alpha mannosidase like 3
ER degradation enhancing alpha mannosidase like protein 3
ER degradation-enhancing alpha-mannosidase-like 3
Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity.
Belongs to the glycosyl hydrolase 47 family. Contains 1 PA (protease associated) domain.
Contains a protease-associated domain (PA) of unknown function.