Recombinant Human eIF2B1 protein (ab124989)

Overview

  • Product name
    Recombinant Human eIF2B1 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MDDKELIEYF KSQMKEDPDM ASAVAAIRTL LEFLKRDKGE TIQGLRANLT SAIETLCGVD SSVAVSSGGE LFLRFISLAS LEYSDYSKCK KIMIERGELF LRRISLSRNK IADLCHTFIK DGATILTHAY SRVVLRVLEA AVAAKKRFSV YVTESQPDLS GKKMAKALCH LNVPVTVVLD AAVGYIMEKA DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP LNQQDVPDKF KYKADTLKVA QTGQDLKEEH PWVDYTAPSL ITLLFTDLGV LTPSAVSDEL IKLYL
    • Molecular weight
      36 kDa including tags
    • Amino acids
      1 to 305
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab124989 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 90 % SDS-PAGE.
    ab124989 is purified by proprietary chromatographic techniques.
  • Form
    Liquid
  • Additional notes
    Although stable at 4°C for 1 week, ab124989 should be stored below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.58% Sodium chloride

General Info

  • Alternative names
    • 26kDa
    • D5Ertd406e
    • EI2BA
    • eIF 2a
    • EIF 2B
    • eIF 2B GDP GTP exchange factor subunit alpha
    • EIF 2Balpha
    • EIF2B
    • EIF2B alpha
    • EIF2B1
    • EIF2BA
    • eukaryotic translation initiation factor 2B subunit 1 alpha
    • Eukaryotic translation initiation factor 2B, alpha
    • eukaryotic translation initiation factor 2B, subunit 1 (alpha, 26kD)
    • Eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
    • MGC117409
    • MGC125868
    • MGC125869
    • MGC6458
    • Translation initiation factor eIF2B subunit alpha
    • zgc:86660
    see all
  • Relevance
    eIF2B1 is one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
  • Cellular localization
    Plasma membrane

References

ab124989 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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