Overview

  • Product name
    Recombinant Human ENPP7 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MRGPAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVD TPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYN TTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQ GVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLDLVTLYFGEPDS TGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMT TVDKRAGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDAL KDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNN GEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPE ANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSSRPLLVMGLLGT VILLSEVA
    • Amino acids
      1 to 458
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab166261 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • ALK SMase
    • Alk-SMase
    • Alkaline sphingomyelin phosphodiesterase
    • E-NPP 7
    • Ectonucleotide pyrophosphatase/phosphodiesterase 7
    • Ectonucleotide pyrophosphatase/phosphodiesterase family member 7
    • ENPP7
    • ENPP7_HUMAN
    • Intestinal alkaline sphingomyelinase
    • NPP-7
    see all
  • Function
    Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.
  • Tissue specificity
    Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
  • Sequence similarities
    Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
  • Post-translational
    modifications
    N-glycosylated; required for activity and transport to the plasma membrane.
  • Cellular localization
    Membrane. Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex.
  • Information by UniProt

Images

  • ab166261 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab166261 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab166261.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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