RelevanceENSA (Alpha endosulfine) is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. The recombinant protein inhibits binding of labeled glibenclamide to beta cell membranes. It also inhibits cloned K(ATP) channel currents and thereby stimulates insulin secretion. It was proposed that endosulfine is an endogenous regulator of the K(ATP) channel, which has a key role in the control of insulin release and, more generally, couples cell metabolism to electrical activity.
Recombinant Human ENSA protein images
SDS-PAGE - ENSA protein (ab38035)
Analysis of ENSA Recombinant Protein, the purified recombinant protein shows a band at 13.9 kDa (calculated). Commassie blue stained gel.
References for Recombinant Human ENSA protein (ab38035)
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