Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVS LVTAELSKDAQASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNS FLHQRIPQSVRILGSLVAILLVFLITAILVKVQLDALPFFVITMIKIVLI NSFGAILQGSLFGLAGLLPASYTAPIMSGQGLAGFFASVAMICAIASGSE LSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKLEGPGEQETKL DLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIF TITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAV FMWPGKDSRWLPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFM AAFAFSNGYLASLCMCFGPKKVKPAEAETAGAIMAFFLCLGLALGAVFSF LFRAIV
    • Molecular weight
      77 kDa including tags
    • Amino acids
      1 to 456

Specifications

Our Abpromise guarantee covers the use of ab152365 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

    SDS-PAGE

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 µg/µl.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Equilibrative NBMPR-sensitive nucleoside transporter
    • equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter
    • Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter
    • Equilibrative nucleoside transporter 1
    • es-type
    • MGC1465
    • MGC3778
    • Nucleoside transporter
    • Nucleoside transporter, es-type
    • OTTHUMP00000016506
    • OTTHUMP00000016507
    • OTTHUMP00000016508
    • OTTHUMP00000016509
    • OTTHUMP00000016510
    • OTTHUMP00000016511
    • OTTHUMP00000016512
    • S29A1_HUMAN
    • Slc29a1
    • solute carrier family 29 (equilibrative nucleoside transporter), member 1
    • solute carrier family 29 (nucleoside transporters), member 1
    • Solute carrier family 29 member 1
    see all
  • Function
    Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs).
  • Tissue specificity
    Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.
  • Sequence similarities
    Belongs to the SLC29A transporter family.
  • Post-translational
    modifications
    Glycosylated.
  • Cellular localization
    Basolateral cell membrane. Apical cell membrane. Predominantly localized in the basolateral membrane in polarised MDCK cells.
  • Information by UniProt

Images

  • 12.5% SDS-PAGE analysis of ab152365 stained with Coomassie Blue.

References

ab152365 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab152365.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up