The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. >98% by SDS-PAGE and HPLC analyses.
Endotoxin level is <0.1 ng per µg of Eotaxin.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
ReconstitutionLyophilized in h2O with no additives. Reconstitute in water to a concentration of 0.1-1µg/µl. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
C-C motif chemokine 11
chemokine (C-C motif) ligand 11
Chemokine C C motif ligand 11
Chemokine CC Motif Ligand 11
Chemokine ligand 11
Eosinophil chemotactic protein
Small inducible cytokine A11
Small inducible cytokine subfamily A (Cys Cys) member 11
small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
Small inducible cytokine subfamily A member 11
Small-inducible cytokine A11
FunctionIn response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Sequence similaritiesBelongs to the intercrine beta (chemokine CC) family.
Post-translational modificationsO-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.