This product is an active protein and may elicit a biological response in vivo, handle with caution.
Eph receptor A3
EPH-like kinase 4
EPH-like tyrosine kinase 1
Ephrin receptor EphA3
Ephrin type-A receptor 3
Human embryo kinase
Human embryo kinase 1
Receptor tyrosine kinase HEK
Testicular tissue protein Li 64
TYRO4 protein tyrosine kinase
Tyrosine protein kinase receptor ETK 1
Tyrosine-protein kinase receptor ETK1
Tyrosine-protein kinase TYRO4
Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.
Widely expressed. Highest level in placenta.
Involvement in disease
Defects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain.