Recombinant human Eph receptor A3 protein (ab84576)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids571 to 983

Specifications

Our Abpromise guarantee covers the use of ab84576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific activity of Eph receptor A3 was determined to be 102 nmol/min/mg as per activity assay protocol.
  • Applications

    Western blot

    Functional Studies

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    Purity was determined to be >90% by densitometry.
  • FormLiquid
  • Additional notes

    ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • AW492086
    • Cek4
    • EC 2.7.10.1
    • EK4
    • End3
    • Eph receptor A3
    • EPH-like kinase 4
    • EPH-like tyrosine kinase 1
    • EPHA3
    • EPHA3_HUMAN
    • Ephrin receptor EphA3
    • Ephrin type-A receptor 3
    • ETK
    • ETK 1
    • ETK1
    • HEK
    • HEK 4
    • HEK4
    • Human embryo kinase
    • Human embryo kinase 1
    • Mek4
    • MGC109882
    • Receptor tyrosine kinase HEK
    • Tyro 4
    • Tyro4
    • TYRO4 protein tyrosine kinase
    • Tyrosine protein kinase receptor ETK 1
    • Tyrosine-protein kinase receptor ETK1
    • Tyrosine-protein kinase TYRO4
    see all
  • FunctionReceptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.
  • Tissue specificityWidely expressed. Highest level in placenta.
  • Involvement in diseaseDefects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].
  • Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
    Contains 2 fibronectin type-III domains.
    Contains 1 protein kinase domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • Cellular localizationSecreted and Cell membrane.
  • Information by UniProt

Recombinant human Eph receptor A3 protein images

  • Specific activity of Eph receptor A3 was determined to be 102 nmol/min/mg as per activity assay protocol.
  • Purity of Eph receptor A3 was determined to be >90% by densitometry, approx. MW 72kDa.

References for Recombinant human Eph receptor A3 protein (ab84576)

ab84576 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab84576.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"