This product is an active protein and may elicit a biological response in vivo, handle with caution.
eph receptor a4
EPH-like kinase 8
Ephrin type-A receptor 4
Receptor protein-tyrosine kinase HEK8
TYRO 1 protein tyrosine kinase
Tyrosine-protein kinase receptor SEK
Tyrosine-protein kinase TYRO1
FunctionReceptor for members of the ephrin-A family. Binds to ephrin-A1, -A4 and -A5. Binds more poorly to ephrin-A2 and -A3. May play a role in a signal transduction process involved in hindbrain pattern formation.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain.
DomainThe protein kinase domain mediates interaction with NGEF/ephexin-1.