This product is an active protein and may elicit a biological response in vivo, handle with caution.
Ephrin receptor EphB4
Ephrin type-B receptor 4
Hepatoma Transmembrane Kinase
Tyrosine-protein kinase receptor HTK
Tyrosine-protein kinase TYRO11
FunctionReceptor for members of the ephrin-B family. Binds to ephrin-B2. May have a role in events mediating differentiation and development.
Tissue specificityAbundantly expressed in placenta and in a range of primary tissues and malignant cell lines. Expressed in fetal, but not adult, brain, and in primitive and myeloid, but not lymphoid, hematopoietic cells.
Sequence similaritiesBelongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain. Contains 1 SAM (sterile alpha motif) domain.