Recombinant Human Estrogen Sulfotransferase protein (ab116431)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionP49888
    • SpeciesHuman
    • SequenceMNSELDYYEK FEEVHGILMY KDFVKYWDNV EAFQARPDDL VIATYPKSGT TWVSEIVYMI YKEGDVEKCK EDVIFNRIPF LECRKENLMN GVKQLDEMNS PRIVKTHLPP ELLPASFWEK DCKIIYLCRN AKDVAVSFYY FFLMVAGHPN PGSLPEFVEK FMQGQVPYGS WYKHVKSWWE KGKSPRVLFL FYEDLKEDIR KEVIKLIHFL ERKPSEELVD RIIHHTSFQE MKNNPSTNYT TLPDEIMNQK LSPFMRKGIT GDWKNHFTVA LNEKFDKHYE QQMKESTLKF RTEILEHHHH HH.
    • Molecular weight36 kDa including tags
    • Amino acids1 to 294
    • TagsHis tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116431 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab116431 was sterile filtered
  • FormLiquid
  • Additional notesStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol

General Info

  • Alternative names
    • EST
    • EST-1
    • EST1
    • Estrogen sulfotransferase
    • estrogen-preferring
    • estrone sulfotransferase
    • ST1E1
    • ST1E1_HUMAN
    • STE
    • Sulfotransferase
    • Sulfotransferase 1E1
    • Sulfotransferase estrogen preferring
    • SULT1E1
    see all
  • FunctionMay control the level of the estrogen receptor by sulfurylating free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 20 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations; however, cortisol, testosterone and dopamine are not sulfated.
  • Tissue specificityLiver, intestine and at lower level in the kidney.
  • Sequence similaritiesBelongs to the sulfotransferase 1 family.
  • Cellular localizationCytoplasm.
  • Information by UniProt

References for Recombinant Human Estrogen Sulfotransferase protein (ab116431)

ab116431 has not yet been referenced specifically in any publications.

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