Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHHSSGLVPRGSHMKAAVDLKPTLTIIKTEKVDLELFPSPDME CADVPLLTPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQWTETHVRDW VMWAVNEFSLKGVDFQKFCMNGAALCALGKDCFLELAPDFVGDILWEHLE ILQKEDVKPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVPPSEFSEPSF ITESYQTLHPISSEELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQEV VTPDNMCMGRTSRGKLGGQDSFESIESYDSCGQEMGKEEKQT
    • Molecular weight
      33 kDa including tags
    • Amino acids
      1 to 272
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab172853 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    HPLC

    SDS-PAGE

  • Endotoxin level
    1.000 Eu/µg
  • Purity
    >95% by SDS-PAGE .
    Purity greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. ab172853 is 0.2 µM filtered.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 0.03% EDTA, 99% PBS

General Info

  • Alternative names
    • Avian erythroblastosis virus E26 (v ets) oncogene homolog 1
    • C ets 1 protein
    • c-ets-1
    • ETS 1
    • Ets protein
    • ETS proto-oncogene 1, transcription factor
    • ETS1
    • ETS1 oncogene
    • ETS1 protein
    • ETS1_HUMAN
    • EWSR 2
    • EWSR2
    • FLJ10768
    • Oncogene ETS1
    • P54
    • Protein C-ets-1
    • v ets avian erythroblastosis virus E2 oncogene homolog
    • v ets avian erythroblastosis virus E2 oncogene homolog 1
    • v ets avian erythroblastosis virus E26 oncogene homolog 1
    • v ets erythroblastosis virus E26 oncogene homolog 1
    • v-ets erythroblastosis virus E26 oncogene homolog 1
    see all
  • Function
    Transcription factor.
  • Sequence similarities
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
    Contains 1 PNT (pointed) domain.
  • Post-translational
    modifications
    Sumoylated on Lys-15 and Lys-227, preferentially by SUMO2; which inhibits transcriptional activity.
    Ubiquitinated; which induces proteasomal degradation.
  • Cellular localization
    Nucleus.
  • Information by UniProt

References

ab172853 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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