Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab82906 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 1x Laemmli Buffer (2.5% Glycerol, 1% SDS, 0.1% Bromophenol blue, 50mM DTT, 25mM Tris HCl, pH 6.8)

General Info

  • Alternative names
    • Fabp6
    • FABP6_HUMAN
    • Fatty acid binding protein 6, ileal (gastrotropin)
    • Fatty acid-binding protein 6
    • Gastrotropin
    • GT
    • I 15P
    • I BABP
    • I BALB
    • I BAP
    • I-15P
    • I-BABP
    • I15P
    • IBABP
    • IBALB
    • IBAP
    • ILBP
    • ILBP3
    • Ileal lipid binding protein
    • Ileal lipid-binding protein
    • ILLBP
    • Intestinal 15 kDa protein
    • Intestinal bile acid binding protein
    • Intestinal bile acid-binding protein
    see all
  • Function
    Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • Tissue specificity
    Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
  • Sequence similarities
    Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • Domain
    Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • Cellular localization
    Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
  • Information by UniProt

References

ab82906 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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