Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMAFTGKFEME SEKNYDEFMK LLGISSDVIE KAHNFKIVTE VQQDGQDFTW SQHYYGGHTM TNKFTVGKES NIQTMGGKTF KATVQMEGGK LVVNFPNYHQ TSEIVGDKLV EVSTIGGVTY ERVSKRLA

Associated products

Specifications

Our Abpromise guarantee covers the use of ab87381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activityab87381 corresponds to isoform 2, 128 aas.
  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • FormLiquid
  • Additional notesab87381 corresponds to isoform 2, 128 aas.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 10% Glycerol, PBS, pH 7.4

General Info

  • Alternative names
    • Fabp6
    • FABP6_HUMAN
    • Fatty acid binding protein 6, ileal (gastrotropin)
    • Fatty acid-binding protein 6
    • Gastrotropin
    • GT
    • I 15P
    • I BABP
    • I BALB
    • I BAP
    • I-15P
    • I-BABP
    • I15P
    • IBABP
    • IBALB
    • IBAP
    • ILBP
    • ILBP3
    • Ileal lipid binding protein
    • Ileal lipid-binding protein
    • ILLBP
    • Intestinal 15 kDa protein
    • Intestinal bile acid binding protein
    • Intestinal bile acid-binding protein
    see all
  • FunctionIleal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.
  • Tissue specificityIsoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.
  • Sequence similaritiesBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • DomainForms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
  • Cellular localizationCytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells.
  • Information by UniProt

Recombinant Human FABP6 protein images

  • ab87381 on 15% SDS-PAGE (3µg)

References for Recombinant Human FABP6 protein (ab87381)

ab87381 has not yet been referenced specifically in any publications.

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