Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MKHHHHHHAS ELIPDAPLSS AAYSIRSIGE RPVLKAPVPK RQKCDHWTPC PSDTYAYRLL SGGGRSKYAK ICFEDNLLMG EQLGNVARGI NIAIVNYVTG NVTATRCFDM YEGDNSGPMT KFIQSAAPKS LLFMVTYDDG STRLNNDAKN AIEALGSKEI RNMKFRSSWV FIAAKGLELP SEIQREKINH SDAKNNRYSG WPAEIQIEGC IPKERS
    • Molecular weight
      24 kDa including tags
    • Amino acids
      30 to 235
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • Endotoxin level
    < 1.000 Eu/µg
  • Purity
    > 90 % SDS-PAGE.

  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.24% Tris, 0.29% Sodium chloride

  • Reconstitution
    Add deionized water (200 µl) to prepare a working stock solution of 0.5 mg/mL

General Info

  • Alternative names
    • 2-21
    • C21orf11
    • C21orf76
    • Cytokine like protein 2 21
    • Cytokine-like protein 2-21
    • Fam3b
    • FAM3B_HUMAN
    • Family with sequence similarity 3 member B
    • ORF9
    • Pancreatic-derived factor
    • PANDER
    • PRED44
    • Protein FAM3B
    see all
  • Function
    Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner. Present in insulin secretory granules and likely cosecreted with insulin.
  • Tissue specificity
    Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.
  • Sequence similarities
    Belongs to the FAM3 family.
  • Post-translational
    modifications
    2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46.
  • Cellular localization
    Secreted. Localized in discrete vesicular and perinuclear structure.
  • Information by UniProt

Recombinant Human FAM3B protein images

  • 12% SDS-PAGE separation of Human FAM3B
    1. reduced and heated sample, 5µg/lane
    2. non-reduced and non-heated sample, 5µg/lane

References for Recombinant Human FAM3B protein (ab113864)

ab113864 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113864.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up